Modeling of adipose/blood partition coefficient for environmental chemicals

Environmental Exposure Modeling for Risk Assessment of Ionizable Organic Chemicals Environmental Exposure Modeling for Risk Assessment of Ionizable Organic Chemicals

Estimation of the soil-water partition coefficient normalized to organic carbon for ionizable organic chemicals.

The sorption of organic electrolytes to soil was investigated. A dataset consisting of 164 electrolytes, composed of 93 acids, 65 bases, and six amphoters, was collected from literature and databases. The partition coefficient log Kow of the neutral molecule and the dissociation constant pKa were calculated by the software ACD/Labs. The Henderson-Hasselbalch equation was applied to calculate di...

EXPERIMENTALl ANALYSIS OF PARTITION COEFFICIENT IN Al-Mg ALLOYS

Because the partition coefficient is one of the most important parameters affecting microsegregation, the aim of this research is to experimentally analyse the partition coefficient in Al-Mg alloys. In order to experimentally measure the partition coefficient, a series of quenching experiments during solidification were carried out. For this purpose binary Al-Mg alloys containing 6.7 and 10.2 w...

Environmental persistence of chemicals.

BACKGROUND The hazard criterion of persistence as it applies to chemicals in the environment is reviewed and discussed. This quantity can not be measured directly in the environment, thus it must be estimated using models that synthesise information on chemical half-lives and partitioning properties, the nature of the environment and how the chemical is released into the environment. MAIN FEA...

Partition of Environmental Chemicals between Maternal and Fetal Blood and Tissues

Passage of environmental chemicals across the placenta has important toxicological consequences, as well as for choosing samples for analysis and for interpreting the results. To obtain systematic data, we collected in 2000 maternal and cord blood, cord tissue, placenta, and milk in connection with births in the Faroe Islands, where exposures to marine contaminants is increased. In 15 sample se...